Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area
نویسندگان
چکیده
منابع مشابه
Microinfusion of Bupropion Inhibits Putative GABAergic Neuronal Activity of the Ventral Tegmental Area
Introduction: The most common interpretation for the mechanisms of antidepression is the increase of the brain monoamine levels such as dopamine (DA). The increase of DA can reduce depression but it can also decrease the monoamine release because of autoreceptor inhibition. Although bupropion can decrease the dopamine release, there is evidence about stimulatory effects of chronic application o...
متن کاملmicroinfusion of bupropion inhibits putative gabaergic neuronal activity of the ventral tegmental area
introduction: the most common interpretation for the mechanisms of antidepression is the increase of the brain monoamine levels such as dopamine (da). the increase of da can reduce depression but it can also decrease the monoamine release because of autoreceptor inhibition. although bupropion can decrease the dopamine release, there is evidence about stimulatory effects of chronic application o...
متن کاملEffects of prefrontal cortical inactivation on neural activity in the ventral tegmental area.
Dopamine (DA) cells have been suggested to signal discrepancies between expected and actual rewards in reinforcement learning. DA cells in the ventral tegmental area (VTA) receive direct projections from the medial prefrontal cortex (mPFC), a structure known to be one of the brain areas that represents expected future rewards. To investigate whether the mPFC contributes to generating reward pre...
متن کاملBehavioral associations of neuronal activity in the ventral tegmental area of the rat.
The ventral tegmental area (VTA) is a central element in a system that mediates the reinforcing properties of natural stimuli (such as food), brain stimulation, and drugs of abuse. Although considerable effort has been applied to understanding how drugs of abuse influence this system, relatively little work has examined its function during conditioned reinforcement tasks in awake, behaving anim...
متن کاملMicroinfusion of Bupropion Inhibits Putative GABAergic Neuronal Activity of the Ventral Tegmental Area
INTRODUCTION The most common interpretation for the mechanisms of antidepression is the increase of the brain monoamine levels such as dopamine (DA). The increase of DA can reduce depression but it can also decrease the monoamine release because of autoreceptor inhibition. Although bupropion can decrease the dopamine release, there is evidence about stimulatory effects of chronic application of...
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ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2015
ISSN: 1047-3211,1460-2199
DOI: 10.1093/cercor/bhv215